Principles of Gene Manipulation and Genomics

The increasing integration between gene manipulation and genomics is embraced in this new book, Principles of Gene Manipulation and Genomics, which brings together for the first time the subjects covered by the best-selling books Principles of Gene Manipulation and Principles of Genome Analysis & Genomics.

• Comprehensively revised, updated and rewritten to encompass within one volume, basic and advanced gene manipulation techniques, genome analysis, genomics, transcriptomics, proteomics and metabolomics
• Includes two new chapters on the applications of genomics
• An accompanying website - www.blackwellpublishing.com/primrose - provides instructional materials for both student and lecturer use, including multiple choice questions, related websites, and all the artwork in a downloadable format.
• An essential reference for upper level undergraduate and graduate students of genetics, genomics, molecular biology and recombinant DNA technology.

In the decade following the publication of the human genome sequence, we have witnessed a revolution in recombinant DNA technology and its applications. The use of gene manipulation techniques on an ever-increasing scale has underpinned numerous advances in biotechnology and medicine, and has vastly increased our understanding of the world around us. Now in its eighth edition, Principles of Gene Manipulation and Genomics embraces this revolution, providing integrated coverage of the techniques used for gene manipulation, genomics, and its related disciplines. As in previous editions, the text covers the basic gene manipulation techniques and then describes recent developments in recombinant DNA technology, genome analysis, functional genomics, and proteomics, bringing these themes together in a final section that discusses how the techniques are applied in the real world.

The eighth edition includes a number of new features such as full-color illustrations throughout, color-coded text boxes in each chapter offering insights into the history, methodology, ethical concerns, and applications of genomic technologies, chapter summaries and thought-provoking end-of-chapter questions. The book is accompanied by a dedicated website providing further instruction and resources for both the student and instructor as well as regular updates on important topics. All art from the book is available to instructors for download from the website.

Principles of Gene Manipulation and Genomics is an accessible and up-to-date guide to this exciting field, and is the essential reference for upper-level undergraduate and graduate students of genetics, genomics, molecular biology, and recombinant DNA technology.

Sandy Primrose was an academic for 10 years and a senior manager in the biotechnology industry for 20 years. He now manages a consultancy practice focused on technology management.

Richard Twyman was an academic for 9 years and now manages a company that provides expert scientific writing and project management services. He is also a Visiting Fellow at the Department of Biology, University of York.