Transgenesis Techniques: Principles and Protocols

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Offers a broad spectrum of practical methods for the generation and analysis of transgenic animals across a comprehensive range of species. Introductory chapters describe ways in which transgenic techniques can be used to address many problems in biological systems. A variety of species is then examined, from invertebrates, to lower vertebrates, to higher vertebrates. Analytical methods are described in depth. Noteworthy features include detailed protocols for the production of transgenic mice and rats, including the most current techniques for isolating ES cells and for producing chimeric mice, and the treatment of sheep as a domestic species--presenting the first detailed treatment of transgenic sheep production to date. Plastic comb-binding. Annotation c. Book News, Inc., Portland, OR (booknews.com)