Biology - Microbiology, Immunology, Biology - Molecular Biology, Biology - Bacteriology, Cytology - General & Miscellaneous, Surgery, Vascular Medicine

Microcirculation in Organ Transplantation

Name: Microcirculation in Organ Transplantation
Author: K. Messmer, Michael D. Menger, W. Land
ISBN: 9783805558495

by K. Messmer, Michael D. Menger, W. Land

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Overview

This volume addresses what has emerged as the major concern of scientists and clinicians since the development of organ transplantation: chronic graft rejection. Seeking to understand this phenomenon, an interdisciplinary group of researchers in microcirculation, cellular biology and experimental and clinical organ transplantation look at endothelial dysfunction at the time of reperfusion as a possible cause. New views and observations suggest that the microcirculatory system, especially its inner endothelium lining, could be damaged by oxygen radical activity, a process leading to chronic organ rejection. Presenting the latest findings, experts consider the importance of such factors as adhesion molecules, atherosclerosis and vascular events, as well as some therapeutic possibilities. Besides providing original and stimulating discussion of the topic, the authors aim to encourage the further investigation needed to shed more light on this complex problem, the bane of many transplant recipients. The work will be of interest to all basic and clinical researchers in microcirculation and transplantation.

Synopsis

This volume addresses what has emerged as the major concern of scientists and clinicians since the development of organ transplantation: chronic graft rejection. Seeking to understand this phenomenon, an interdisciplinary group of researchers in microcirculation, cellular biology and experimental and clinical organ transplantation look at endothelial dysfunction at the time of reperfusion as a possible cause. New views and observations suggest that the microcirculatory system, especially its inner endothelium lining, could be damaged by oxygen radical activity, a process leading to chronic organ rejection. Presenting the latest findings, experts consider the importance of such factors as adhesion molecules, atherosclerosis and vascular events, as well as some therapeutic possibilities.
Besides providing original and stimulating discussion of the topic, the authors aim to encourage the further investigation needed to shed more light on this complex problem, the bane of many transplant recipients. The work will be of interest to all basic and clinical researchers in microcirculation and transplantation.