Case Files: Biochemistry

Relating the clinical setting to basic science data, the 45 patient cases in this study aid for the USMLE Step 1 illustrate the principles of gene expression and protein synthesis, metabolism and ATP, carbohydrate and lipid metabolism, and biochemical endocrinology. Each case describes the presenting symptoms and diagnosis, explains the biochemical mechanisms underlying the disease, and provides several multiple choice questions. Annotation ©2005 Book News, Inc., Portland, OR

Doody Review Services

Reviewer:Hazem M. Hallak, PhD(Thomas Jefferson University)
Description:This case-based book is designed to apply the basic sciences to clinical medicine. Each one of the 51 cases includes a clinical problem that introduces a basic science question. The first edition was published in 2005.
Purpose:The basic sciences in general, and biochemistry in particular, are always difficult subjects for medical students to master. This book simplifies biochemistry and makes it more engaging and interesting. Each case study is explained well and includes very detailed answers.
Audience:This would be useful to medical students who are studying for the USMLE Step 1. The 51 cases include high yield concepts tested on the exam, presented in a format that is very easy to understand. The book is written by 17 highly qualified contributors.
Features:Each case includes a clinical problem and the related basic science questions. The answers are organized into four parts, each delineating a clinical and basic science problem, multiple choice questions, and a list of important points addressed by the case. The book is focused, covering all of the important topics likely to be found on the USMLE. It includes the necessary basic science detail while concentrating on the clinically relevant information. Numerous charts and graphs help with visual learning. The authors have done an outstanding job of summarizing and choosing subjects that are important to know for the USMLE Step 1.
Assessment:What separates this book from others is the way it addresses the topics tested on the exam in just enough detail. It engages students eager to apply preclinical concepts to clinical problems. Undoubtedly, this book will help medical students master the connection between biochemistry and the clinical diseases they are likely to encounter on the wards.

Eugene C. Toy, MD is a dual certified family physician and ob/gyn and is Academic Chief and Program Director for the Obstetrics and Gynecology residency at The Methodist Hospital in Houston, Texas, where he is also actively involved in teaching medical students. He oversees the ob/gyn clerkship at Christus-St. Joseph Hospital.

William E. Seifert, Jr., PhD is Senior Lecturer and Medical Biochemistry Course Director in the Department of Biochemistry and Molecular Biology at The University of Texas—Houston Medical School.

Henry W. Strobel, PhDis Professor in the Department of Biochemistry and Molecular Biology; Assistant Dean for Student Affairs; and Associate Dean for Faculty Affairs at The University of Texas—Houston Medical School.

Konrad P. Harms, MD is Associate Program Director and Director of Academic Development for the Obstetrics and Gynecology Residency Program at The Methodist Hospital in Houston, Texas.